试题与答案

羟氨苄青霉素() A.抗菌谱窄,不耐酸,不耐青霉素酶 B.抗菌谱窄,不耐酸,耐青霉素

题型:单项选择题 B1型题

题目:

羟氨苄青霉素()

A.抗菌谱窄,不耐酸,不耐青霉素酶

B.抗菌谱窄,不耐酸,耐青霉素酶

C.抗菌谱窄,耐酸,耐青霉素酶

D.抗菌谱广,不耐酸,不耐青霉素酶

E.抗菌谱广,耐酸,不耐青霉素酶

答案:

参考答案:E

解析:氨苄青霉素半合成的广谱青霉素类抗生素。白色或类白色粉末或结晶。无臭,味微苦,易溶于水,微溶于乙醇,不溶于乙醚。不耐酶,对酸稳定。1题选E。青霉素G不能耐受耐药菌株(如耐药金葡)所产生的酶,易被其破坏,不耐酸,且其抗菌谱较窄,主要对革兰氏阳性菌有效。2题选A。羧苄青霉素抗菌谱广,不耐酸,对产酶金黄色葡萄球菌无效。3题选D。羟氨苄青霉素为广谱半合成青霉素,在氨苄西林的苯环上加1个对位羟基,使其在胃酸中更加稳定,口服吸收更安全;不耐青霉素酶。4题选E。

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